A side-by-side look at plasma concentration curves, therapeutic windows, and what actually happens when you take your medication late.
Its 24-hour half-life would normally make it forgiving — like lamotrigine. But its narrow therapeutic index (only 25% margin to toxicity) turns that long half-life into a trap.
Half-life tells you how fast levels change. Therapeutic index tells you how much that change matters. You need both to know if timing is critical.
| Medication | 2 h late | 6 h late | Skipped entirely |
|---|